Caputo finds difficulty in his new role as warden after the new staff and inmates settle in. The pre-existing inmates are rallied back into camp while Alex and Whitehill stay back to resolve a rather big problem. Chapman tries to prove top dog in the overcrowded prison, Red isn't happy with her new work schedule, and Crazy Eyes finds a new love interest.
The mothers in the prison celebrate mothers day with their children. A new counselor is hired and that threatens Healy. Alex returns in bad shape. Crazy Eyes has trouble grasping what happened to Vee. Daya struggles with her lies about her baby. Nichols fights with her inner addict.
Travis Block, a shadowy Government agent who specializes in removing operatives whose covers have been exposed, uncovers a deadly conspiracy within his own ranks that reaches the highest echelons of power.
All is not what it seems when Lucy and Dane conspire a breakout from their mythical island cells.